Insights into targeting LKB1 in tumorigenesis

Genetic alterations to serine-threonine kinase 11 (STK11) have been implicated in Peutz-Jeghers syndrome and tumorigenesis.Further exploration of the context-specific roles of liver kinase B1 (LKB1; encoded by STK11) observed that it regulates AMP-activated protein kinase (AMPK) and AMPK-related kinases.Given that both migration and proliferation a

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Beyond extraction accuracy: addressing the quality of geographical named entity through advanced recognition and correction models using a modified BERT framework

In the realm of geospatial services and applications, the accuracy of address information is of utmost importance.Traditional methods of data collection, being both labor-intensive and costly, have prompted researchers to turn to Volunteered Geographic Information (VGI) for the extraction of Geographical Named Entity (GNE).Notwithstanding, prior st

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Mandibular dental arch short and long-term spontaneous dentoalveolar changes after slow or rapid maxillary expansion: a systematic review

ABSTRACT Objective: The aim of this systematic review was to analyze the short and long-term spontaneous dentoalveolar changes of the mandibular dental arch after slow (SME) or rapid (RME) maxillary expansion in the mixed and early permanent dentitions.Methods: An electronic search was performed in the following databases: PubMed/Medline, Cochrane

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Impact of Different Sugar Syrups on the Development of the Fat Body in Worker Bees (Apis mellifera macedonica)

Global climate change, intensive agriculture, and anthropogenic pollution adversely affect flowering plants and the vitality of bee colonies.In nutritional stress conditions, bees deplete the food reserves of their fat body to sustain colony life.Beekeepers play a critical JUNIPER BERRY role by providing supplemental nutrient solutions.This study e

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